Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Amagwiritsidwa ntchito kwa odwala akuluakulu omwe ali ndi opaleshoni yosankha m'chiuno kapena mawondo kuti ateteze venous thrombosis (VTE).
Amagwiritsidwa ntchito poletsa kapena kuchepetsa mapangidwe a thrombosis, deep vein thrombosis (DVT) ndi pulmonary embolism (PE) pambuyo pa opaleshoni ya m'chiuno kapena mawondo.
Mlingo woyenera ndi oral rivaroxaban 10mg, kamodzi pa tsiku.Rivaroxaban 10mg akhoza kutengedwa ndi chakudya kapena yekha.Mapiritsi a Rivaroxaban 15mg kapena 20mg ayenera kutengedwa ndi chakudya.
muyezo: usp40
Chiwerengero: 99-102%
Kunja: ufa woyera
Phukusi: 25kg / ng'oma
Tengani 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) ndizomwe zimayambira .Pambuyo pa condensation, cyclization, aminolysis ndi acylation, crude rivaroxaban imapezeka, ndipo rivaroxaban yomalizidwa imayengedwa.
Kukonzekera: Izi mankhwala ndi wofiira filimu TACHIMATA piritsi.
Zida:
Pakatikati pa piritsi: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, sodium lauryl sulfate, magnesium stearate.
Kupaka: polyethylene glycol, hypromellose, titanium dioxide, iron oxide red
Rivaroxaban ndi mankhwala osankhidwa kwambiri, omwe amaletsa mwachindunji factor Xa.Kupyolera mu kuletsa kosankha komanso kupikisana kwa chinthu chaulere ndi chomangika cha Xa ndi ntchito ya prothrombin, talikitsa mbale yanthawi ya thromboplastin (PT) ndi nthawi ya prothrombin (aPTT) motengera mlingo, zomwe zimatha kusokoneza mathithi a coagulation. kuletsa kupanga thrombin ndi thrombosis.Rivaroxaban samaletsa thrombin (activating factor Ⅱ), komanso sizinatsimikizidwe kuti zimakhudza mapulateleti.
Kusiyana kofunikira pakati pa rivaroxaban ndi fondaparinux/heparin ndikuti sikufuna kutenga nawo gawo kwa antithrombin III ndipo imatha kutsutsa mwachindunji Xa;pamene heparin imafuna antithrombin III kuti igwire ntchito, ndipo ilibe mphamvu pa factor Xa mu prothrombin complex.
JIN DUN Medical ali ndiKuyenerera kwa ISO ndikukwaniritsa miyezo ya GMP yopanga, olemba ntchito akatswiri apakhomo ndi akunja opangira mankhwala omwe ali ndi luso lotsogolera R&D yamakampani.
Ubwino wa TECHNOL OGY
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Kusintha kwa Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Kukonzekeranso
● Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Zida
Labu yathu ili ndi zida zosiyanasiyana zoyesera ndi kuyesa, monga: NMR (Bruker 400M), HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope ...
Gulu la R&D
Jindun Medical ili ndi gulu la akatswiri a R&D, ndipo amagwiritsa ntchito akatswiri ambiri opangira mankhwala apakhomo ndi akunja kuti aziwongolera R&D, kupangitsa kuti kaphatikizidwe kathu kakhale kolondola komanso kothandiza.
Tathandiza makampani angapo apamwamba apanyumba azachipatala, mongaHansoh, Hengrui ndi HEC Pharm.Apa tikuwonetsa gawo lawo.
Kusintha Mwamakonda Mlandu Woyamba:
Cas No.: 110351-94-5
Mwamakonda Mlandu Wachiwiri:
Cas No.: 144848-24-8
Kusintha Mwamakonda Mlandu Wachitatu:
Cas No.: 200636-54-0
1.Sinthani Mwamakonda Anu Apakati kapena ma API.Monga momwe tafotokozera pamwambapa, makasitomala ali ndi zofuna za Intermediates kapena ma API, ndipo sangapeze zomwe zimafunikira pamsika, ndiye titha kuthandiza Kusintha Mwamakonda Anu.
2.Kukhathamiritsa kwa Zinthu Zakale.Gulu lathu lithandizira Kukulitsa ndi kukonza zopanga zotere zomwe njira yake ndi yakale, mtengo wopangira ndi wokwera, ndipo magwiridwe ake ndi otsika.Titha kupereka zolembedwa zonse za kutengerapo kwaukadaulo ndi kukonza njira, kuthandiza kasitomala kuti apange bwino.
Kuchokera ku zolinga za mankhwala kupita ku INDs, JIN DUN Medical amakupatsiraninjira imodzi yokhayokha ya R&D.
JIN DUN Medical amaumirira kupanga gulu lokhala ndi maloto, kupanga zinthu zolemekezeka, zanzeru, zolimba, ndikupita zonse kuti mukhale bwenzi lodalirika komanso bwenzi lamakasitomala!
![Casp ungin Acetate;Caspofungin acetate;Cancidas;Caspofungin acetate [USAN:BAN:JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)