PriceList for High Quality Antiviral Entecavir Powder CAS 142217-69-4 ndi Mtengo Wabwino Kwambiri

Timaperekanso makampani opanga zinthu kapena ntchito komanso ophatikiza ndege.Tili ndi malo athu opangira zinthu komanso ofesi yopezera zinthu.Titha kukupatsirani pafupifupi mitundu yonse yazogulitsa zofanana ndi zomwe timagulitsa pa PriceList for High Quality Antiviral Entecavir Powder CAS 142217-69-4 yokhala ndi Mtengo Wabwino Kwambiri, Tipitiliza kuyesetsa kukulitsa kampani yathu ndikupereka zinthu zabwino kwambiri. ndi mitengo mwamakani.Kufunsa kulikonse kapena ndemanga zimayamikiridwa kwambiri.Kumbukirani kutigwira mwaufulu.
Timaperekanso makampani opanga zinthu kapena ntchito komanso ophatikiza ndege.Tili ndi malo athu opangira zinthu komanso ofesi yopezera zinthu.Titha kukupatsirani pafupifupi mtundu uliwonse wa malonda ofanana ndi mitundu yathu yazogulitsaChina Entecavir ndi 142217-69-4, Tikulandira mwansangala makasitomala apakhomo ndi akunja kudzacheza ndi kampani yathu ndikukambirana zamalonda.Kampani yathu nthawi zonse imaumirira pa mfundo ya "zabwino, mtengo wololera, ntchito yapamwamba kwambiri".Ndife okonzeka kupanga mgwirizano wautali, waubwenzi komanso wopindulitsa ndi inu.

Entecavir (SQ 34676;BMS 200475) ndi HBV Inhibitor yosankha komanso yothandiza.M'maselo a HepG2 EC50 mtengo ndi 3.75 nM.Mankhwala aposachedwa kwambiri othana ndi matenda a chiwindi a mtundu wa B komanso odana ndi Edzi.

Mphamvu ya Entecavir

Mankhwalawa ndi guanine nucleoside analogue, omwe ali ndi cholepheretsa pa hepatitis B virus (HBV) polymerase.Itha kukhala phosphorylated kukhala triphosphate yogwira, ndipo theka la moyo wa triphosphate mu cell ndi maola 15.Mwa kupikisana ndi HBV polymerase's natural substrate deoxyguanosine triphosphate, entecavir triphosphate ikhoza kulepheretsa ntchito zonse zitatu za viral polymerase (reverse transcriptase): (1) HBV polymerase initiation;(2) pregenomic mRNA Kupanga kwa chingwe choyipa cha reverse transcript;(3) Kaphatikizidwe ka chingwe chabwino cha HBV DNA.The inhibitory constant (Ki) ya entecavir triphosphate pa HBV DNA polymerase ndi 0.0012μM.Entecavir triphosphate ili ndi mphamvu yofooka yolepheretsa selo α, β, δ DNA polymerase ndi mitochondrial γ DNA polymerase, ndi Ki mtengo wa 18 mpaka 160 μM.

Thupi ndi mankhwala katundu wa Entecavir

Entecavir Customs

Zina Zowonjezera:

Qu Qiang (PhD muchipatala chachipatala, Dipatimenti ya Pharmacy, Xiangya Hospital, Central South University) ndi Wang Ruoguang (Doctor of Medicine, postdoctoral in biology, Changsha Ruoguang Medical Research Center) analembanso kuti: mu regimen ya entecavir, entecavir ikhoza kutengedwa. kwa zaka zingapo kapena zaka 10.Kuposa zaka.Ndipo ingagwiritsidwe ntchito ndi amayi apakati, kusonyeza chitetezo chabwino.

Potengera njira zomwe zimadziwika kuti mamolekyulu a pharmacological, Entecavir ikhoza kukhala ndi anti-spectrum antiviral effect, osati yolimbana ndi HBV yokha.

Nthawi zambiri timagwiritsa ntchito Entecavir kuti tithetse matenda opatsirana pogwiritsa ntchito mavairasi kuchipatala, ndipo zotsatira zake ndi zodabwitsa.

Pakadali pano, pakuwunikanso kwa odwala opitilira 500 a COVID19 ku Hubei (malo), munthu m'modzi yekha adatenga entecavir.Nthawi yolembera inali kumayambiriro kwa Januware, ndiyeno mankhwalawa adayimitsidwa.

Pomwe akuthandizira ogwira ntchito zachipatala ku Hubei, madotolo ena akumidzi, kapena magulu omwe ali pachiwopsezo chachikulu, omwe akugwiritsa ntchito Entecavir kupewa COVID19, palibe vuto la matenda.Anthu omwe akuganiziridwa kuti akumwa entecavir, palibe amene wapita patsogolo kuti apezeke ndi COVID19.

Mavuto a Patent:

Pali njira ziwiri, 06 ndondomeko ndi ndondomeko 89.Kutha kwa patent kwa njira ya 06 ndikoyambika kwambiri (kutha mu 2023)!Ngakhale kuti mtengo wa ndondomekoyi ndi wotsika, khalidweli ndi labwino, ndipo ogwira ntchito akhoza kukhala amphamvu, malangizo aumwini: Kwa zomera za mankhwala, gwiritsani ntchito ndondomeko ya 06 kuti musakhale odzikuza;kwa makampani opanga mankhwala, musatengeke ndipo musakhale owopsa kwambiri.

Mu 2014, Chia Tai Tianqing adapeza malonda a pachaka a 10 biliyoni ya yuan podalira mankhwala osokoneza bongo monga entecavir, omwe entecavir anali 20%.

Popeza kuti entecavir inavomerezedwa kuti ilowe mu 2005, makampani oposa 100 ogulitsa mankhwala apakhomo apempha kuti alembetse mankhwalawa;pakati pawo, makampani ovomerezeka opangira mankhwala akuphatikizapo Jiangsu Zhengda Tianqing Pharmaceutical (kutsanzira koyamba), Hainan Zhonghe Pharmaceutical, ndi Fujian Guangxi Pharmaceutical Co., Ltd. Shengtang Pharmaceutical, Jiangxi Qingfeng Pharmaceutical, Suzhou Dawnrays Pharmaceutical, Shanghai Downrays Pharmaceutical, Singchung. Lukang, Zhejiang Huasheng Biopharmaceutical, Changzhi Sanbao Biochemical.

Pharmaceutical, Anhui Baker Biopharmaceutical, Hunan Concord Pharmaceutical Industry, Beijing Xiehe Pharmaceutical Factory, Beijing Baiao Pharmaceutical, Xinlitai Pharmaceutical, Dongyangguang, etc.;kupitilira kuyambira tsiku la mgwirizano, mankhwalawa adalowa m'mitundu yodziwika bwino kuyambira 2007.

Timaperekanso makampani opanga zinthu kapena ntchito komanso ophatikiza ndege.Tili ndi malo athu opangira zinthu komanso ofesi yopezera zinthu.Titha kukupatsirani pafupifupi mitundu yonse yazogulitsa zofanana ndi zomwe timagulitsa pa PriceList for High Quality Antiviral Entecavir Powder CAS 142217-69-4 yokhala ndi Mtengo Wabwino Kwambiri, Tipitiliza kuyesetsa kukulitsa kampani yathu ndikupereka zinthu zabwino kwambiri. ndi mitengo mwamakani.Kufunsa kulikonse kapena ndemanga zimayamikiridwa kwambiri.Kumbukirani kutigwira mwaufulu.
PriceList kwaChina Entecavir ndi 142217-69-4, Tikulandira mwansangala makasitomala apakhomo ndi akunja kudzacheza ndi kampani yathu ndikukambirana zamalonda.Kampani yathu nthawi zonse imaumirira pa mfundo ya "zabwino, mtengo wololera, ntchito yapamwamba kwambiri".Ndife okonzeka kupanga mgwirizano wautali, waubwenzi komanso wopindulitsa ndi inu.