pentamethylene bis [1-(3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate

pentamethylene bis [1-(3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate imagwiritsidwa ntchito ngati pakati pa Cisatracurium besylate.
Cisatracurium besylate ndi mchere wa benzene sulfonate wa atracurium.Ndi mtundu wa zotsitsimula zopanga zopanda depolarizing zomwe zimakhala ndi gawo lofanana ndi tubocurarine.Ili ndi nthawi yoyambira mphindi imodzi ndi nthawi ya mphindi 15.Mlingo wa mankhwalawa sukhudza mtima, chiwindi ndi impso.Ilibenso katundu wodzikundikira.Itha kupangitsanso kutulutsa histamine ikagwiritsidwa ntchito pamlingo waukulu.Pofuna kupumula kwa minofu kapena kupuma komwe kumafunika pa opaleshoni, poyerekeza ndi mankhwala amakono akuluakulu ochepetsa minofu, cisatracurium besylate sichimapangidwa ndi chiwindi kapena impso, ndipo imakhala ndi kukhazikika kwa mtima;zotsatira zake za kupumula kwa minofu ndizolimba katatu monga atracurium popanda zotsatira za mtima.Cisatracurium besylate imagwiritsidwa ntchito makamaka ku anesthesia wamba, ndipo imatha kugwiritsidwa ntchito kwambiri pochiza, kuchiza matenda a chiwindi ndi impso, omwe amagwiritsidwa ntchito pa opaleshoni ya mtima ndi odwala okalamba ndi ana.
Poyerekeza ndi atracurium, mankhwalawa alibe zotsatira zoyipa zomwe zimatengera kutulutsidwa kwa histamine;komabe, choyipa ndichakuti odwala omwe ali ndi vuto la chiwindi ndi impso ayenera kuyang'anira mosamala.
Kuyambira 1996 kwa nthawi yoyamba pamene mankhwalawa adalowa mumsika ku UK, mayiko akunja adagwiritsa ntchito pang'onopang'ono kuti alowe m'malo mwa vecuronium ndi atracurium monga njira zambiri zotsitsimula minofu yachipatala.