Chiwerengero cha anthu odwala khansa ya prostate chikuchulukirachulukira chaka ndi chaka, ndipo chakhala chimodzi mwa zinthu zomwe zimapha kwambiri thanzi la amuna okalamba.Pakadali pano, China yakhazikitsa miyezo yowunikira khansa ya prostate, koma ikufunikabe kupitiliza kulimbikitsa kudziwitsa anthu za kuyezetsa.Ye Dingwei, wachiwiri kwa purezidenti wa Chipatala cha Cancer chogwirizana ndi Fudan University komanso wamkulu wa dipatimenti ya urology, adati pamsonkhano waposachedwa wa akatswiri a khansa ya prostate yomwe idachitika ku Guangzhou kuti China ikufunikabe kulimbikitsa udindo wake wotsogola pakufufuza kwamankhwala kwapadziko lonse lapansi. Kupititsa patsogolo mayesero achipatala, kuti apititse patsogolo kukula ndi kukhazikitsidwa kwa mankhwala atsopano komanso kupindulitsa odwala ambiri ku China.
Khansara ya Prostate ndi chotupa choopsa cha epithelial chomwe chimapezeka mu prostate ndipo ndi chotupa choopsa kwambiri mu urogenital system yamphongo.Chifukwa alibe zizindikiro zenizeni zachipatala kumayambiriro, nthawi zambiri amalakwitsa ndi madokotala kapena odwala chifukwa cha prostatic hypertrophy kapena hyperplasia, ndipo ngakhale odwala ambiri samabwera kukaonana ndi dokotala mpaka atakhala ndi zizindikiro za metastatic monga kupweteka kwa mafupa.Zotsatira zake, pafupifupi 70% ya odwala khansa ya prostate ku China ndi omwe ali ndi khansa ya prostate yodziwika bwino kwambiri akapezeka, osalandira chithandizo chokwanira komanso osazindikira.Komanso, chiwerengero cha odwala khansa ya prostate chimawonjezeka ndi zaka, kukwera mofulumira pambuyo pa zaka 50, ndipo chiwerengero cha anthu omwe amafa komanso kufa kwa zaka 85 chimafika pachimake.Pansi pakukula kwa ukalamba ku China, chiwerengero chonse cha anthu omwe ali ndi khansa ya prostate ku China chidzakwera.
Ye Dingwei adati kuchuluka kwa anthu omwe ali ndi khansa ya prostate ku China kwadutsa zotupa zina zolimba, ndipo chiwerengero cha anthu omwe amafa chikukwera kwambiri.Panthawi imodzimodziyo, zaka zisanu za kupulumuka kwa khansa ya prostate ku China ndi zosakwana 70%, pamene ku Ulaya ndi United States, makamaka United States, chiwerengero cha kupulumuka kwa zaka zisanu chili pafupi ndi 100%.“Chomwe chikuchititsa zimenezi n’chakuti kuzindikira za kuyezetsa magazi m’dziko lonse la China n’kofookabe, ndipo palibe mgwirizano pa kuzindikira kuti magulu amene ali pachiopsezo chachikulu ayenera kukayezetsa PSA zaka ziwiri zilizonse;ndipo odwala ena sanalandire chithandizo choyenera, ndipo njira yonse yoyendetsera khansa ya prostate ku China ikufunikabe kuwongolera. "
Monga makhansa ambiri, kuzindikira koyambirira, kuzindikira ndi kuchiza khansa ya prostate kumatha kukulitsa moyo.Zeng Hao, membala wa Gulu Lofufuza la Achinyamata komanso Mlembi Wamkulu wa Urology Nthambi ya Chinese Medical Association, adati anthu aku Europe ndi America amawona kufunikira kwakukulu pakupewa ndi kuchiza khansa ya prostate, ndipo kuchuluka kwa kuyezetsa khansa ya prostate ndikocheperako. apamwamba, omwe amalola odwala ambiri omwe ali ndi khansa yoyambirira ya prostate kuti alandire mwayi wolandira chithandizo chabwino, pomwe anthu aku China sakudziwa za kuyezetsa matenda, ndipo odwala ambiri amakhala otsogola komanso opezeka ndi khansa ya prostate yomwe imapezeka.
"Pakadali kusiyana kwakukulu pakati pa odwala khansa ya prostate ku China ndi Europe ndi United States kuyambira pachiyambi mpaka pakuzindikira matenda mpaka kuchiza matenda.Chifukwa chake, kupewa ndi kuchiza khansa ya prostate ku China kuli ndi njira yayitali," adatero Zeng Hao.
Kodi mungasinthe bwanji mawonekedwe?Ye Dingwei adanena kuti choyamba ndi kufalitsa chidziwitso cha kuwunika koyambirira.Odwala a Prostate azaka zopitilira 50 omwe ali pachiwopsezo chachikulu ayenera kuyang'aniridwa ngati ali ndi kachilombo ka prostate specific antigen (PSA) zaka ziwiri zilizonse.Chachiwiri, chithandizo cha khansa ya prostate chiyenera kuyang'anitsitsa kwambiri chithandizo chamankhwala olondola komanso ndondomeko yonse.Chachitatu, pochiza, tiyenera kulabadira chithandizo chamitundumitundu (MDT) kwa odwala omwe ali ndi khansa ya prostate pakati komanso mochedwa.Kupyolera mu mgwirizano wa njira zingapo zomwe zili pamwambazi, chiwerengero cha kupulumuka kwa khansa ya prostate ku China chingakhale bwino kwambiri mtsogolomu.
"Tikadali ndi njira yayitali yoti tipitirire kuwongolera kuchuluka kwa matenda odziwika bwino komanso kulondola kwa kuzindikira."Zeng Hao adanena kuti vuto lalikulu pakuwongolera matenda a msanga komanso chithandizo chamankhwala msanga ndikuti m'maphunziro azachipatala, kufunikira kwa zolembera zotupa ndizofunikira kwambiri, ndipo kuzindikira kwa chotupa kuyenera kuphatikizidwa ndi kujambula kapena kubaya biopsy kuti mumve zambiri. matenda, koma zaka zapakatikati odwala khansa ya prostate ali pakati pa zaka 67 ndi 70, Odwala okalamba otere amavomereza zochepa za puncture biopsy.
Pakalipano, njira zochiritsira za khansa ya prostate zimaphatikizapo opaleshoni, radiotherapy, chemotherapy ndi endocrine therapy, yomwe endocrine therapy ndiyo njira yaikulu yothandizira khansa ya prostate.
Ye Dingwei adanena kuti zotsatira za ASCO-GU zomwe zangotulutsidwa kumene chaka chino zasonyeza kuti mankhwala ophatikizira omwe amapangidwa ndi PARP inhibitor Talazoparib ndi enzalutamide apeza zotsatira zabwino mu mayesero a chipatala cha III, ndipo nthawi yonse yopulumuka yakhala yabwino kwambiri. zotsatira zabwino zoyembekezeredwa, kuyembekezera kusintha moyo wonse wa odwala metastatic castration kusamva khansa ya prostate mtsogolo.
"Pali mipata ya msika komanso zosowa zachipatala zomwe sizinakwaniritsidwe poyambitsa mankhwala atsopano m'dziko lathu."Ye Dingwei adanena kuti akuyembekeza kufulumizitsa kukhazikitsidwa kwa mankhwala atsopano, komanso akuyembekeza kuti gulu lachipatala la China likhoza kutenga nawo mbali pa mayesero a zachipatala a mankhwala padziko lonse, kusunga mlingo womwewo ndi kafukufuku wakunja ndi chitukuko ndi msika, ndikugwira ntchito limodzi kuti abweretse zambiri. njira zatsopano zochizira odwala, sinthani kuchuluka kwa matenda am'mimba komanso kupulumuka kwathunthu.
JinDun Medicalali ndi mgwirizano wanthawi yayitali wofufuza zasayansi komanso kulumikiza ukadaulo ndi mayunivesite aku China.Ndi chithandizo chamankhwala cholemera cha Jiangsu, ili ndi ubale wautali wamalonda ndi India, Southeast Asia, South Korea, Japan ndi misika ina.Imaperekanso ntchito zamsika ndi zogulitsa munjira yonse kuyambira apakatikati mpaka kumaliza API.Gwiritsani ntchito zomwe zasonkhanitsidwa za Yangshi Chemical mu chemistry ya fluorine kuti mupereke ntchito zapadera zosinthira makonda kwa anzanu.Perekani njira zatsopano zogwirira ntchito ndi ntchito zofufuza zonyansa kwa makasitomala.
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Nthawi yotumiza: Mar-20-2023