Guanosine
Guanosine
Guanosine amagwiritsidwa ntchito ngati wapakatikati wa Valaciclovir.
Valacyclovir ndi guanine analogue antiviral mankhwala.Amagwiritsidwa ntchito pochiza matenda a herpes simplex ndi herpes zoster matenda opatsirana pogonana.Izi ndi kalambulabwalo wa acyclovir.Imatengeka mwachangu pambuyo pa makonzedwe amkamwa ndipo imasandulika kukhala acyclovir m'thupi.Mphamvu yake yoletsa ma virus imaseweredwa ndi acyclovir.Pambuyo acyclovir akulowa nsungu HIV maselo, amapikisana ndi deoxynucleoside kwa HIV thymidine deoxynucleoside kinase kapena selo kinase, ndi mankhwala phosphorylated mu adamulowetsa acyclic guanosine triphosphate.Monga gawo lapansi la kugawanika kwa kachilomboka, acyclovir amapikisana ndi deoxyguanine triphosphate kwa kachilombo ka DNA polymerase, yomwe imalepheretsa kaphatikizidwe ka DNA ndikuwonetsa antiviral kwenikweni.The sapha mavairasi oyambitsa ntchito ya mankhwala mu vivo ndi bwino kuposa acyclovir, ndi mankhwala index a nsungu simplex HIV mtundu I ndi mtundu II ndi 42,91% ndi 30,13% apamwamba kuposa acyclovir motero.Ilinso ndi mphamvu yochiritsa kwambiri pa varicella zoster virus.
JIN DUN Medical ali ndiKuyenerera kwa ISO ndikukwaniritsa miyezo ya GMP yopanga, olemba ntchito akatswiri apakhomo ndi akunja opangira mankhwala omwe ali ndi luso lotsogolera R&D yamakampani.
Ubwino wa TECHNOL OGY
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Kusintha kwa Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Kukonzekeranso
● Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Zida
Labu yathu ili ndi zida zosiyanasiyana zoyesera ndi kuyesa, monga: NMR (Bruker 400M), HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope ...
Gulu la R&D
Jindun Medical ili ndi gulu la akatswiri a R&D, ndipo amagwiritsa ntchito akatswiri ambiri opangira mankhwala apakhomo ndi akunja kuti aziwongolera R&D, kupangitsa kuti kaphatikizidwe kathu kakhale kolondola komanso kothandiza.
Tathandiza makampani angapo apamwamba apanyumba azachipatala, mongaHansoh, Hengrui ndi HEC Pharm.Apa tikuwonetsa gawo lawo.
Kusintha Mwamakonda Mlandu Woyamba:
Cas No.: 110351-94-5
Mwamakonda Mlandu Wachiwiri:
Cas No.: 144848-24-8
Kusintha Mwamakonda Mlandu Wachitatu:
Cas No.: 200636-54-0
1.Sinthani Mwamakonda Anu Apakati kapena ma API.Monga momwe tafotokozera pamwambapa, makasitomala ali ndi zofuna za Intermediates kapena ma API, ndipo sangapeze zomwe zimafunikira pamsika, ndiye titha kuthandiza Kusintha Mwamakonda Anu.
2.Kukhathamiritsa kwa Zinthu Zakale.Gulu lathu lithandizira Kukulitsa ndi kukonza zopanga zotere zomwe njira yake ndi yakale, mtengo wopangira ndi wokwera, ndipo magwiridwe ake ndi otsika.Titha kupereka zolembedwa zonse za kutengerapo kwaukadaulo ndi kukonza njira, kuthandiza kasitomala kuti apange bwino.
Kuchokera ku zolinga za mankhwala kupita ku INDs, JIN DUN Medical amakupatsiraninjira imodzi yokhayokha ya R&D.
JIN DUN Medical amaumirira kupanga gulu lokhala ndi maloto, kupanga zinthu zolemekezeka, zanzeru, zolimba, ndikupita zonse kuti mukhale bwenzi lodalirika komanso bwenzi lamakasitomala!
