Cyclopropyl 2-fluorobenzyl ketone

Cyclopropyl 2-fluorobenzyl ketone amagwiritsidwa ntchito ngati wapakatikati wa Prasugrel.
Prasugrel ndi thiophenopyridine antiplatelet yopangidwa ndi Eli Lilly ndi daiichisankyo, wopanga mankhwala ku Japan.Ndi mankhwala oyambilira.Amapanga molekyulu yogwira ntchito pambuyo pa kagayidwe ka cytochrome P450 m'chiwindi ndikuphatikiza ndi mapulateleti P2Y12 cholandirira kuti agwire ntchito yolimbana ndi kuphatikizika kwa mapulateleti.Kafukufuku wazachipatala watsimikizira kuti 60 mg imakhala ndi anticoagulant yabwinoko kuposa 300 mg wamba ndi 600 mg yowonjezereka ya clopidogrel, yomwe imatha kuchepetsa chiwopsezo cha matenda amtima, sitiroko ndi kufa chifukwa cha matenda amtima ndi 20%. , zotsatira zabwino zochizira, kukana mankhwala abwino ndi bioavailability, ndi kawopsedwe kochepa.