4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-methoxy-2-methyl-5-pyrimidinamin;
4-chloro-n- (4,5-dihydro-1h-imidazol-2-yl) -6-methoxy-2-methyl-5-pyrimidinamin;
Zimagwira ntchito polimbikitsa chapakati presynaptic alpha 2- receptors.Zotsatira zake za hypotensive ndizofanana ndi nifedipine, calcium antagonist, ndi captopril, ACE inhibitor.Kwa matenda oopsa kwambiri.
Izi mankhwala ayenera kutengera mfundo ya payekha mankhwala.Nthawi zambiri amayamba pa mlingo wotsika kwambiri, ndiye kuti, 0.2mg, kamodzi patsiku, wotengedwa m'mawa.Kusintha kwa mlingo kuyenera kuchitidwa pakadutsa milungu itatu mpaka zotsatira zokhutiritsa zitapezeka.Mlingo wamba ndi 0.2mg kamodzi, kawiri pa tsiku (m'mawa ndi madzulo).Pazipita mlingo pa nthawi sayenera upambana 0,4mg, ndipo pazipita tsiku mlingo sayenera upambana 0,6mg.Kwa odwala omwe ali ndi vuto laimpso wofatsa kapena zolimbitsa thupi, mlingo umodzi sayenera kupitirira 0,2 mg kapena tsiku lililonse sayenera kupitirira 0,4 mg.
Izi ndi α2-receptor agonist, yomwe ndi imidazoline antihypertensive mankhwala.Amagwiritsidwa ntchito pochiza matenda oopsa komanso oopsa kwambiri komanso achiwiri.
Chifukwa zimalepheretsa katulutsidwe ndi kayendedwe ka m'mimba, ndizoyeneranso kwa odwala omwe ali ndi matenda a zilonda zam'mimba.Kuphatikizika kwa mankhwalawa ndi okodzetsa kumatha kusintha kwambiri magwiridwe antchito.Ndi mankhwala amphamvu apakati a antihypertensive komanso mzere wachiwiri wa antihypertensive.Imaperekedwa makamaka kwanuko mu ophthalmology.Mankhwalawa ali ndi zotsatira zochepetsera kuthamanga kwa intraocular, ndipo samakhudza wophunzira ndi kusintha kwa maso.Ikhoza kusokoneza mitsempha yamagazi m'maso, kuchepetsa kupanga nthabwala zamadzimadzi, ndi kukwaniritsa zotsatira zochepetsera kuthamanga kwa intraocular.Zimayamba kugwira ntchito pakangopita mphindi 15 diso likatsika ndipo zimatha kukhalabe ndi mphamvu kwa maola pafupifupi 8.
Standard:EP10
Zoyeserera:97.5-102.0%
Kunja:White kapena pafupifupi pamene ufa
Phukusi:1kg/thumba kapena malinga ndi makasitomala
JIN DUN Medical ali ndiKuyenerera kwa ISO ndikukwaniritsa miyezo ya GMP yopanga, olemba ntchito akatswiri apakhomo ndi akunja opangira mankhwala omwe ali ndi luso lotsogolera R&D yamakampani.
Ubwino wa TECHNOL OGY
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Kusintha kwa Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Kukonzekeranso
● Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Zida
Labu yathu ili ndi zida zosiyanasiyana zoyesera ndi kuyesa, monga: NMR (Bruker 400M), HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope ...
Gulu la R&D
Jindun Medical ili ndi gulu la akatswiri a R&D, ndipo amagwiritsa ntchito akatswiri ambiri opangira mankhwala apakhomo ndi akunja kuti aziwongolera R&D, kupangitsa kuti kaphatikizidwe kathu kakhale kolondola komanso kothandiza.
Tathandiza makampani angapo apamwamba apanyumba azachipatala, mongaHansoh, Hengrui ndi HEC Pharm.Apa tikuwonetsa gawo lawo.
Kusintha Mwamakonda Mlandu Woyamba:
Cas No.: 110351-94-5
Mwamakonda Mlandu Wachiwiri:
Cas No.: 144848-24-8
Kusintha Mwamakonda Mlandu Wachitatu:
Cas No.: 200636-54-0
1.Sinthani Mwamakonda Anu Apakati kapena ma API.Monga momwe tafotokozera pamwambapa, makasitomala ali ndi zofuna za Intermediates kapena ma API, ndipo sangapeze zomwe zimafunikira pamsika, ndiye titha kuthandiza Kusintha Mwamakonda Anu.
2.Kukhathamiritsa kwa Zinthu Zakale.Gulu lathu lithandizira Kukulitsa ndi kukonza zopanga zotere zomwe njira yake ndi yakale, mtengo wopangira ndi wokwera, ndipo magwiridwe ake ndi otsika.Titha kupereka zolembedwa zonse za kutengerapo kwaukadaulo ndi kukonza njira, kuthandiza kasitomala kuti apange bwino.
Kuchokera ku zolinga za mankhwala kupita ku INDs, JIN DUN Medical amakupatsiraninjira imodzi yokhayokha ya R&D.
JIN DUN Medical amaumirira kupanga gulu lokhala ndi maloto, kupanga zinthu zolemekezeka, zanzeru, zolimba, ndikupita zonse kuti mukhale bwenzi lodalirika komanso bwenzi lamakasitomala!
