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2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

Kufotokozera Kwachidule:

CAS noChithunzi: 153012-08-9

Chemical katundu: Gemcitabine Intermediates


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Ntchito

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate imagwiritsidwa ntchito ngati pakati pa Gemcitabine.
Gemcitabine ndi analogue ya pyrimidine nucleotide, yomwe ndi ya anti metabolic anticancer.Zitha kulepheretsa kupita patsogolo kwa kaphatikizidwe ka DNA munthawi inayake, ndiye kuti, gawo la S.Iwo ali ndi makhalidwe a sipekitiramu lonse anticancer, wapadera limagwirira kanthu, otsika kawopsedwe, palibe kukana mtanda ndi mankhwala ena chemotherapeutic ndipo palibe superposition wa kawopsedwe.Masiku ano, gemcitabine yavomerezedwa kuti igwiritsidwe ntchito m'maiko opitilira 90, kukhala mankhwala oyamba ochizira khansa ya m'mapapo yopanda maselo ang'onoang'ono komanso "golide" wochizira khansa ya kapamba.


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