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1-Bromo-2-methoxy-3-nitro-benzene

1-Bromo-2-methoxy-3-nitro-benzene

Kufotokozera Kwachidule:

CAS noChithunzi: 98775-19-0

Chemical katundu: Eltrombopag Intermediates


Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Ntchito

1-Bromo-2-methoxy-3-nitro-benzene amagwiritsidwa ntchito ngati wapakatikati wa Eltrombopag.
Eltrombopag, yopangidwa ndi GlaxoSmithKline (GSK) ku UK ndipo pambuyo pake idapangidwa limodzi ndi Novartis ku Switzerland, ndiye woyamba komanso wovomerezeka wa agonist ang'onoang'ono omwe si peptide TPO receptor agonist padziko lapansi.Eltrombopag idavomerezedwa ndi US FDA mu 2008 pochiza idiopathic thrombocytopenic purpura (ITP), komanso mu 2014 pochiza aplastic anemia (AA).Ndiwonso mankhwala oyamba ovomerezedwa ndi US FDA pochiza AA m'zaka 30 zaposachedwa.
Mu december2012, US FDA inavomereza Eltrombopag zochizira thrombocytopenia odwala matenda a chiwindi C (CHC), kuti odwala matenda a chiwindi C ndi osauka matenda chifukwa otsika kupatsidwa zinthu za m`mwazi kuwerenga akhoza kuyamba ndi kusunga interferon zochokera muyezo mankhwala kwa matenda a chiwindi.Pa february3, 2014, GlaxoSmithKline adalengeza kuti FDA idapereka chithandizo chamankhwala chopambana cha Eltrombopag pochiza hemopenia kwa odwala omwe ali ndi chemicalbook aplastic anemia (SAA) omwe sanayankhe mokwanira ku immunotherapy.Pa Ogasiti 24, 2015, US FDA idavomereza Eltrombopag kuti azichiza thrombocytopenia mwa akulu ndi ana azaka za 1 ndi kupitilira omwe ali ndi matenda osachiritsika a immune thrombocytopenia (ITP) omwe alibe yankho lokwanira ku corticosteroids, immunoglobulins kapena splenectomy.Pa january4, 2018, Eltrombopag idavomerezedwa kuti ilembedwe ku China kuti ichiritse primary immune thrombocytopenia (ITP).

Resource-integrated Product Line

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Satifiketi

JIN DUN Medical ali ndiKuyenerera kwa ISO ndikukwaniritsa miyezo ya GMP yopanga, olemba ntchito akatswiri apakhomo ndi akunja opangira mankhwala omwe ali ndi luso lotsogolera R&D yamakampani.

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Ubwino pa Medical Customization

Ubwino wa TECHNOL OGY
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Kusintha kwa Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
●Kukonzekeranso
● Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction

JIN DUN R&D

Zida

Labu yathu ili ndi zida zosiyanasiyana zoyesera ndi kuyesa, monga: NMR (Bruker 400M), HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope ...

Gulu la R&D

Jindun Medical ili ndi gulu la akatswiri a R&D, ndipo amagwiritsa ntchito akatswiri ambiri opangira mankhwala apakhomo ndi akunja kuti aziwongolera R&D, kupangitsa kuti kaphatikizidwe kathu kakhale kolondola komanso kothandiza.

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Kugawana Mlandu

Tathandiza makampani angapo apamwamba apanyumba azachipatala, mongaHansoh, Hengrui ndi HEC Pharm.Apa tikuwonetsa gawo lawo.

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Kusintha Mwamakonda Mlandu Woyamba:

Cas No.: 110351-94-5

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Mwamakonda Mlandu Wachiwiri:

Cas No.: 144848-24-8

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Kusintha Mwamakonda Mlandu Wachitatu:

Cas No.: 200636-54-0

Cooperation Mode

1.Sinthani Mwamakonda Anu Apakati kapena ma API.Monga momwe tafotokozera pamwambapa, makasitomala ali ndi zofuna za Intermediates kapena ma API, ndipo sangapeze zomwe zimafunikira pamsika, ndiye titha kuthandiza Kusintha Mwamakonda Anu.

2.Kukhathamiritsa kwa Zinthu Zakale.Gulu lathu lithandizira Kukulitsa ndi kukonza zopanga zotere zomwe njira yake ndi yakale, mtengo wopangira ndi wokwera, ndipo magwiridwe ake ndi otsika.Titha kupereka zolembedwa zonse za kutengerapo kwaukadaulo ndi kukonza njira, kuthandiza kasitomala kuti apange bwino.

Kuchokera ku zolinga za mankhwala kupita ku INDs, JIN DUN Medical amakupatsiraninjira imodzi yokhayokha ya R&D.

JIN DUN Medical amaumirira kupanga gulu lokhala ndi maloto, kupanga zinthu zolemekezeka, zanzeru, zolimba, ndikupita zonse kuti mukhale bwenzi lodalirika komanso bwenzi lamakasitomala!


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